1.   As you get older, your bones become more brittle.

2.   As your baby grows bigger, his bones become less pliable.

3.   Once oestrogen levels fall, the bone becomes less dense and strong and more liable to fracture.

4.   As myeloma advances, bones become brittle.

5.   Bones become fragile.

6.   A synthetic version is used to treat osteoporosis, a disease that causes bones to become porous and brittle.

7.   But in osteoporosis, the balance is tipped in favor of osteoblasts and the bone becomes weaker and more fragile.

8.   Calcium deficiency puts people, especially older white women, at greater risk for osteoporosis, a disease in which the bones become extremely brittle and susceptible to fractures.

9.   In osteoporosis, the balance is tipped in favor of osteoclasts and the bone becomes weaker and more fragile.